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story.lead_photo.caption This image released by Universal Pictures shows Dr. John Dolittle, portrayed by Robert Downey Jr., right, with Jip, voiced by Tom Holland, in a scene from "Dolittle." (Universal Pictures via AP)

Dr. Dolittle, who favored animals and shunned humans, was on to something.

The century of human history since Hugh Lofting, in 1920, created his eccentric veterinarian character has only made Dolittle a more astute fictional figure, and a natural candidate for big-screen resurrection. Aquaman can talk to the fishes, but Dolittle has the ability to converse with all fauna.

But if they could speak, no realm of the animal kingdom — no penguin, parakeet or panda — would have anything good to say about Stephen Gaghan’s “Dolittle,” a big-budget train wreck in which things go so awry that it can’t even be said to be strictly for the dogs.

“Dolittle,” starring Robert Downey Jr., arrives just weeks after the advent of “Cats,” another Universal Pictures release likewise stuffed with computer generated animals. “Dolittle” is a more harmless and whimsical family entertainment, less likely to provoke nightmares than the digitally furred felines of Tom Hooper’s Andrew Lloyd Webber adaptation. But, just the same, the two films together could be the worst setback for animalia since global warming, or at least “Howard the Duck.”

It’s tempting to think: Well, it can’t be that bad. Who doesn’t like Downey and animals? At the very least, you would think, no amount of special effects can completely dilute such a vibrant and clever actor. He was even good in the Marvel movies!

But perhaps the biggest disappointment of “Dolittle” isn’t the incoherent storyline, the suffocating CGI or the unfunny stable of celebrity-voiced creatures. It’s that Downey’s personality doesn’t come through at all, either a victim of the surrounding mess or a party to it.

Seemingly going for a tamer Johnny Depp-as-Jack Sparrow-styled performance, Downey dons a vaguely Welsh accent, deepening his voice in a hushed tone. Worse, much of his dialogue seems to have been overdubbed, a likely component of the movie’s extensive reworking in post-production and reshoots. It distances Downey — he sounds literally elsewhere — in a fantasy that’s already plenty adrift.

The movie is based on the second of Lofting’s books, “The Voyages of Doctor Dolittle.” He created the character first to, in letters home from the World War I front, entertain his children. Dolittle first appeared on screen in the 1967 movie, with Rex Harrison, and later in a series begun in 1998, with Eddie Murphy.

This incarnation has an unlikely zookeeper in Gaghan, who won an Oscar for his screenplay to Steven Soderbergh’s “Traffic” and directed the labyrinthine geopolitical thriller “Syriana.” He last directed “Gold,” with Matthew McConaughey, a disappointing dramatization of the Bre-X Minerals swindle of the 1990s.

“Doolitle,” a Universal Pictures release, is rated PG by the Motion Picture Association of America for some action, rude humor and brief language. Running time: 101 minutes. One star out of four.

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