Texas A&M's offense was practically unstoppable, with and without Johnny Manziel. That Aggies defense needed all the help it could get against Rice.
Johnny Football packed three touchdown passes into less than a half of work for the seveth-ranked Aggies, who beat Rice 52-31 in College Station, Texas, on Saturday.
Manziel was held out of the first half because of what the school said was an "inadvertent" violation of NCAA rules involving signing autographs.
Manziel was one of more than a half dozen players serving suspensions Saturday.
Cornerbacks Deshazor Everett and De'Vante Harris, defensive tackle Kirby Ennis, defensive end Gavin Stansbury and linebacker Steven Jenkins, all starters, sat out for Texas A&M. Everett returned in the second half, then was ejected for a targeting penalty and he'll miss the first half of next week's game against Sam Houston State, too. Backup safety Floyd Raven was also suspended for this game.
The suspensions of Harris, Stansbury, Jenkins and receiver Edward Pope are for two games and were announced just minutes before kickoff, meaning they'll be back for top-ranked Alabama on Sept. 14.
No. 1 ALABAMA 35, VIRGINIA TECH 10
ATLANTA (AP) - Christion Jones became the first Alabama player since at least the 1940s to have two returns for touchdowns, Vinnie Sunseri brought back an interception for another TD, and the Crimson Tide overcame a sluggish offensive performance to beat Virginia Tech.
Jones scored on a 72-yard punt return less than 2 minutes into the game, then scooted loose on a kickoff for a 94-yard touchdown that led the Crimson Tide (1-0) to a win that could've been much tougher to start its quest for an unprecedented third straight national title.
For good measure, the junior receiver also hauled in a 38-yard touchdown pass late in the third quarter to blow it open against the Hokies (0-1), who largely shut down AJ McCarron and Alabama's highly touted offense.
No. 2 OHIO STATE 40, BUFFALO 20
COLUMBUS, Ohio (AP) - Braxton Miller threw two touchdown passes before fighting leg cramps and Jordan Hall ran for two more scores to lead Ohio State to a victory over Buffalo in the season opener for both teams.
The Buckeyes, striving for a crisper start from coach Urban Meyer's debut in 2012, led 23-0 after the first quarter before the Bulls made things interesting. Joe Licata threw two TD passes and linebacker Kahlil Mack returned a Miller interception 45 yards to make it 30-20 in the third quarter.
Miller was sidelined a second time with cramps and sub Kenny Guiton promptly tossed a 21-yard TD pass to Chris Fields.
Hall had a career-high 159 yards rushing, scoring on runs of 37 and 49 yards.
No. 3 OREGON 66, NICHOLLS 3
EUGENE, Ore. (AP) - Marcus Mariota threw a touchdown pass and ran for two additional scores and the Oregon Ducks made easy work of lower-tier Nicholls.
Mariota, who set an Oregon record with 38 touchdowns last season as a redshirt freshman, completed 12 of 21 passes for 234 yards before sitting after the third quarter when the Ducks had built a 45-3 lead.
Mariota also ran for 113 yards for his second career game with more than 100 yards rushing.
De'Anthony Thomas ran for 128 yards and two more touchdowns for Oregon in the debut of new head coach Mark Helfrich.
Helfrich, the team's former offensive coordinator, was promoted when Chip Kelly left the Ducks in January for the NFL's Philadelphia Eagles.
No. 8 CLEMSON 38, No. 5 GEORGIA 35
CLEMSON, S.C. (AP) - Tajh Boyd threw for three touchdowns and rushed for two others, Clemson's defense sacked Aaron Murray four times and the Tigers stung the Bulldogs.
Boyd had scoring passes of 77 yards to Sammy Watkins, 24 yards to Zac Brooks and 9 yards to Stanton Seckinger. Boyd also added TD runs of 4 and 2 yards to win the lone matchup of top 10 teams in college football's opening weekend.
The Tigers took the lead for good, 31-28, on Chandler Catanzaro's 24-yard field goal in the third quarter. Georgia had a chip-shot try for a tying kick on its next possession, but couldn't get if off after Nathan Theus' bad snap .
Two series later, Boyd led a 12-play, 87-yard TD drive that ended with tight end Seckinger tip-toeing the sidelines to get in.
Georgia's Todd Gurley ran for 154 yards and two touchdowns.
No. 7 TEXAS A&M 52, RICE 31
COLLEGE STATION, Texas (AP) - After serving his first-half suspension, Heisman Trophy winner Johnny Manziel threw three TD passes and scrambled for 19 yards - ran his mouth a bit, too - as Texas A&M posted a lopsided win over Rice.
Manziel was sitting out because of what the school said was an "inadvertent" violation of NCAA rules involving signing autographs.
His first touchdown came on a 23-yard pass to Mike Evans on A&M's second drive of the half.
Shortly before that, he got into it with a Rice defender, appearing to mimic signing an autograph while getting up from a tackle. He ended his day by getting yanked following an unsportsmanlike conduct penalty for pointing at the scoreboard after a TD pass in the fourth quarter.
He was replaced by Matt Joeckel on A&M's last drive.
No. 10 FLORIDA 24, TOLEDO 6
GAINESVILLE, Fla. (AP) - Mack Brown had a career day, Jeff Driskel was efficient and Florida opened the season with a victory over Toledo.
Brown ran 25 times for 112 yards and two touchdowns. Driskel completed 17 of 22 passes for 153 yards and a score. And Florida's defense, which ranked fifth in the country in 2012, looked every bit as good as last year's version despite losing eight starters and its coordinator.
The Gators controlled both lines of scrimmage, opening holes for Brown and keeping steady pressure on Toledo's experienced spread offense. It was exactly the style of play Florida has become known for under third-year coach Will Muschamp. No flashiness. Few highlight-reel plays. But a win in the end.
It was Florida's 24th consecutive season-opening victory, the second-longest active streak in the country. Only Nebraska (27) has a longer current run.
No. 12 LSU 37, No. 20 TCU 27
ARLINGTON, Texas (AP) - Terrence Magee ran for two touchdowns in the second half, Zach Mettenberger threw for 251 yards with a key late score and LSU held on for a victory.
Odell Beckham's 75-yard kickoff return set up a 20-yard TD pass from Mettenberger to Jarvis Landry with 6 minutes left.
All in all, despite a crucial fumble and a three-and-out in the fourth quarter that kept the game uncomfortably close, the Tigers' first game with new offensive coordinator Cam Cameron calling the plays provided a promising start to the season.
And that replenished defense after losing a team-record eight players to the NFL draft came up with some key plays.
B.J. Catalon returned a kickoff 100 yards for a touchdown and scored on a 26-yard run for TCU.
No. 13 OKLAHOMA STATE 21, MISSISSIPPI STATE 3
HOUSTON (AP) - J.W. Walsh threw for 135 yards and ran for another 125 and a touchdown to lead the Oklahoma State Cowboys to a win over the Mississippi State in the Texas Kickoff.
Walsh finished 18 of 27 after relieving starter Clint Chelf on the Cowboys' third series. Jeremy Smith rushed for 102 yards and two touchdowns on 15 carries for Oklahoma State (1-0), which piled up 432 yards on offense after struggling for most of the first half.
Tyler Russell 10 of 16 for 133 yards before being helped off the field and taken to the locker room in the third quarter after being brought down on a scramble. Dak Prescott replaced Russell, throwing for 89 yards on seven of 17 passing.
LaDarius Perkins rushed for 50 yards on 16 carries and caught three passes for 52 yards for the Bulldogs (0-1).
No. 14 NOTRE DAME 28, TEMPLE 6
SOUTH BEND, Ind. (AP) - Tommy Rees threw a pair of 32-yard touchdown passes to DaVaris Daniels, a 66-yard scoring pass to Troy Niklas and Notre Dame had three quick scoring drives en route to a victory over Temple.
The 14th-ranked Irish jumped to a 14-0 lead on a pair of three-play drives on its opening two possessions and appeared headed for a blowout. But when the Notre Dame offense stalled, Temple squandered a pair of scoring chances, with Jim Cooper Jr. missing a pair of field goals. An unsettled feeling settled in at Notre Dame Stadium when Kenny Harper scored on a 1-yard run to cut the lead to 14-6. The Irish regained control, however, with Niklas' TD with 43 seconds left in the half.
The victory by the Irish (1-0) was the 200th career win for coach Brian Kelly. The Owls (0-1) fell to 2-76 all-time against ranked opponents.
No. 15 TEXAS 56, NEW MEXICO STATE 7
AUSTIN, Texas (AP) - David Ash threw four touchdown passes and ran for another as Texas shook off a slow start to roll.
Ash threw two interceptions in the second quarter and the Longhorns' new up-tempo offense stalled as the Aggies took a 7-0 lead. Ash then connected on touchdown passes of 54 and 66 yards to John Harris and Daje (duh-jay) Johnson in the final two minutes of the first half.
In the third quarter, Ash turned a scramble into a 55-yard touchdown and passed to Malcolm Brown for a 74-yard score. After falling behind, Texas (1-0) scored 35 points on 15 snaps and finished with a school-record 715 total yards with Ash accounting for 434.
Andrew McDonald was 32-of-46 passing with one touchdown, but also had two turnovers for the Aggies (0-1), who went 1-11 last season.
No. 16 OKLAHOMA 34, LOUISANA-MONROE 0
NORMAN, Okla. (AP) - Trevor Knight rushed for 103 yards on 13 carries and threw three touchdown passes - two to Jalen Saunders - in his first start and Oklahoma beat Louisiana-Monroe.
Oklahoma gave coach Bob Stoops his 150th career win, putting him seven behind Barry Switzer on the Sooners' career coaching wins list. Oklahoma is 5-0 under Stoops in August games and 14-1 in home openers, having lost only to Texas Christian in 2005.
Knight became the first Oklahoma quarterback to rush for 100 or more yards in a game since Jason White had 117 yards rushing against Kansas on Oct. 13, 2001.
Louisiana-Monroe upset then-No. 8 Arkansas on the road to open the 2012 season, but the Warhawks didn't get untracked offensively against a revamped Oklahoma defense. The Warhawks crossed midfield only twice and recorded only nine first downs and 166 yards of offense.
No. 17 MICHIGAN 59, CENTRAL MICHIGAN 9
ANN ARBOR, Mich. (AP) - Devin Gardner ran for two touchdowns and threw for another in the first half as Michigan went on to beat Central Michigan.
It was the highest-scoring opener for the Wolverines (1-0) since 1905, when they beat Ohio Wesleyan 65-0. They will face a tougher test against No. 14 Notre Dame next week at home in a prime-time game.
The Chippewas (0-1) fell behind 35-6 at halftime Saturday. After they gave up five straight TDs, Ron Coluzzi's third field goal made it 56-9 with 3:12 left in the game.
Gardner was 10 of 15 for 162 yards with a 16-yard TD pass to Jeremy Gallon and two interceptions. He ran for a 22-yard score midway through the first quarter when Michigan led by just four points and had a 4-yard TD on the ground late in the first half.
No. 18 NEBRASKA 37, WYOMING 34
LINCOLN, Neb. (AP) - Ameer Abdullah and Imani Cross each ran for more than 100 yards, Taylor Martinez passed for three touchdowns and Nebraska survived two late turnovers to defeat Wyoming.
The Cornhuskers, who won their nation-leading 28th straight opener, scored on four of five possessions after trailing 14-10 early in the second quarter and then had to hang on as Wyoming made it a game to the end.
The Cowboys converted two late Nebraska turnovers into touchdowns to pull within 37-34 with 1:32 left. Nebraska recovered the onside kick after Brett Smith's 47-yard TD pass to Robert Herron.
Wyoming's defense held, and the Cowboys got the ball back on their 6 with 1:07 to play, but time ran out on them before they could even get to midfield.
WASHINGTON 38, No. 19 BOISE STATE 6
SEATTLE (AP) - Keith Price threw a pair of third-quarter touchdown passes to become the school's all-time leader, and Washington returned renovated Husky Stadium with a stunning blowout of Boise Stat.
It was the worst loss in Chris Petersen's tenure as the Broncos head coach.
Price was intercepted on his first pass in the Huskies newly renovated home on the shores of Lake Washington. And he was nearly perfect from there, the first step in putting a disappointing 2012 season in the past.
Price completed 23 of 31 passes for 324 yards. He found Kasen Williams on a 19-yard TD on Washington's first possession of the second half and his 18-yard strike to Josh Perkins gave Washington a 24-6 lead late in the third quarter. It was Price's 56th career touchdown, passing Cody Pickett as Washington's all-time leader.
No. 21 UCLA 58, NEVADA 20
PASADENA, Calif. (AP) - Brett Hundley passed for 274 yards and two touchdowns and rushed for two more scores, leading UCLA's second-half surge.
Jordon James rushed for 155 yards and a touchdown, and Phillip Ruhl returned a blocked punt for a short touchdown as UCLA thoroughly spoiled the debut of Nevada coach Brian Polian with a 41-point second half.
Shaq Evans had six receptions for 81 yards and a score, and Malcolm Jones caught a late TD pass during a dominant effort by the UCLA offense, which piled up 647 total yards.
Cody Fajardo passed for 164 yards and rushed for two TDs, but the Wolf Pack couldn't keep up in their debut under Polian, the 38-year-old picked to replace Hall of Fame coach Chris Ault.
No. 22 NORTHWESTERN 44, CALIFORNIA 30
BERKELEY, Calif. (AP) - Collin Ellis returned two interceptions after deflected passes for touchdowns to help Northwestern spoil Sonny Dykes' debut as California coach.
Ellis had a 56-yard return in the third quarter and then put the Wildcats (1-0) in control when he took another one back 40 yards midway through the fourth to open a 10-point lead.
Those were rare blemishes on an otherwise strong debut by Jared Goff, who became the first true freshman to start the season opener for the Golden Bears (0-1). Goff went 38 for 63 for 445 yards and two touchdowns, and Cal also scored on a fake field goal on the opening drive in an entertaining start to Dykes' tenure.
No. 23 WISCONSIN 45, MASSACHUSETTS 0
MADISON, Wis. (AP) - Melvin Gordon ran for 144 yards, James White added 143 and Wisconsin's revamped defense pitched a shutout of Massachusetts in coach Gary Andersen's debut.
Gordon and White padded their totals by each running for touchdowns of at least 51 yards for the Badgers, who didn't stray far from their trademark rushing attack with the defensive-minded Andersen now pacing the sideline.
Joel Stave overcame a slow start at quarterback to connect with Jared Abbrederis for two long touchdown passes in the second half.
UMass was simply overmatched against the Big Ten's three-time defending champion. The Minutemen are only in their second year as a major college program, and they had to play Saturday with running back Jordan Broadnax and tight end Rob Blanchflower out with injuries.
Stacey Bedell finished with 70 yards on 19 carries for UMass.
EASTERN WASHINGTON 49, No. 25 OREGON STATE 46
CORVALLIS, Ore. (AP) - Vernon Adams passed for 411 yards and ran for 107 and the go-ahead score with 18 seconds left as Eastern Washington upset Oregon State to become the third FCS team to beat a ranked FBS team.
Adams overwhelmed the Beavers in a performance in sure to attract attention around the nation. He threw for four touchdowns and ran for two, completing 23 of 30 passes despite leaving the game twice - once with cramping and a second time after taking a hard hit near the sideline.
Adams returned, though, and scored on a 2-yard run to put the Eagles up 49-46. It was the first time a team from the Football Championship Subdivision has defeated a ranked team from the Football Bowl Subdivision since James Madison beat Virginia Tech in September 2010.
Sean Mannion threw for 422 yards and Brandin Cooks had 13 catches for 196 yards for the Beavers.