HOUSTON (AP) - Jed Lowrie broke up a combined no-hit bid by Cleveland with a one-out home run in the ninth inning Thursday, and the Indians beat the Houston Astros 5-1.
Indians starter Trevor Bauer was pulled after throwing 111 pitches through six innings. He struck out a career-high 11 and walked five.
Relievers Kyle Crockett and Scott Atchison each pitched a scoreless inning before Nick Hagadone took over. Hagadone struck out Chris Carter to begin the ninth. Lowrie then sent a 94 mph fastball far over the left-center field wall for Houston's only hit.
The Indians have not had a no-hitter since Len Baker threw a perfect game in 1981 against Toronto.
Bauer and the Cleveland relievers teamed to strike out 16 while walking seven.
Roberto Perez and Jose Ramirez homered for Cleveland.
Astros starter Asher Wojciechowski (0-1) gave up four runs and eight hits in four-plus innings in his major league debut.
BLUE JAYS 6, YANKEES 3
NEW YORK (AP) - Alex Rodriguez hit his first home run since serving a yearlong drug suspension, but Toronto beat New York for eccentric rookie Daniel Norris' first win in the majors.
Edwin Encarnacion homered and the Blue Jays got RBI singles from Jose Reyes and Kevin Pillar in a four-run second inning against CC Sabathia.
The Blue Jays took two of three in the season-opening series, boosting their record at Yankee Stadium to 7-30 since May 24, 2011.
On another raw and rainy night in the Bronx, Rodriguez led off the sixth with a drive into the left-field seats for his 655th career homer. It was A-Rod's first home run since Sept. 20, 2013. The three-time MVP ranks fifth on the career list, five behind Willie Mays.
Mark Teixeira homered off Norris (1-0) two batters later, cutting it to 5-3, but Encarnacion homered off Esmil Rogers in the eighth. Miguel Castro pitched a perfect ninth for his first career save.
TIGERS 7, TWINS 1
DETROIT (AP) - Shane Greene helped Detroit set the modern AL record for the longest shutout streak to start a season at 24 innings in a victory over Minnesota.
After the start was delayed by rain for over 3 1/2 hours, new Twins manager Paul Molitor's team dropped to 0-3. And when Minnesota scored its lone run in the seventh, it was unearned.
Detroit broke the AL mark of 22 innings set by the 1947 Chicago White Sox, STATS said. The longest such streak in the majors since 1912 is 32 innings by the 1963 St. Louis Cardinals.
Greene (1-0) gave up four hits in eight innings and struck out five. Kyle Gibson (0-1) allowed six runs on eight hits and five walks in 3 2/3 innings.
The Twins scored when Joe Mauer walked and Kennys Vargas hit a double that was misplayed by left fielder Yoenis Cespedes. The franchise's previous worst run drought at the start of a year was 20 innings by the 1940 Washington Senators.
METS 6, NATIONALS 3
WASHINGTON (AP) - Matt Harvey was dynamic in his return from Tommy John surgery, outpitching Stephen Strasburg with six scoreless innings, regularly reaching 97 mph and striking out nine to lead New York past Washington.
The 26-year-old Harvey hadn't appeared in a regular-season game since Aug. 24, 2013, nearly 20 months ago; he had the ligament-replacement operation on his right elbow that October.
The righty powered fastballs by hitters - he struck out Bryce Harper three times swinging at high heat - and mixed in sharp breaking balls. Harvey (1-0) gave up four hits and one walk.
Strasburg (0-1) allowed six runs - three earned - and nine hits in 5 1-3 innings. The Mets batted around in the third to score four runs, three unearned because of shortstop Ian Desmond's third error of the season. Strasburg left after giving up David Wright's two-run single in the sixth.
GIANTS 1, PADRES 0, 12 INNINGS
SAN DIEGO (AP) - Pinch-hitter Justin Maxwell had an RBI single with two outs in the 12th inning and San Francisco spoiled new-look San Diego's home opener.
The Giants won despite being held to six hits by six pitchers. The lone run came against Nick Vincent (0-1) consisted of an error, an intentional walk and Maxwell's single.
Brandon Crawford reached with one out when backpedaling shortstop Clint Barmes dropped his pop fly in shallow left. With two outs, Gregor Blanco was intentionally walked before Maxwell, batting for winner George Kontos, singled up the middle.
Kontos (1-0) allowed one hit and struck out two in 1 2-3 innings.
Santiago Casilla pitched the 12th for his third save in three chances.
ROYALS 4, WHITE SOX 1
KANSAS CITY, Mo. (AP) - Edinson Volquez dazzled for eight innings in his Royals debut, Lorenzo Cain made a pair of spectacular catches after driving in a run, and Kansas City beat Chicago to finish a season-opening sweep.
Salvador Perez added a two-run homer, Kendrys Morales also drove in a run and the AL champion Royals improved to 3-0 for the first time since an opening sweep of Detroit in 2008.
Volquez (1-0) allowed four hits, including Alexei Ramirez's RBI single. Greg Holland worked a perfect ninth for his second save in less than 24 hours.
The Royals pounded Chicago counterpart John Danks (0-1), who had been 7-0 in 16 career starts against them. Danks allowed all four runs on seven hits and a walk in 5 2-3 innings.
RANGERS 10, ATHLETICS 1
OAKLAND, Calif. (AP) - Shin-Soo Choo hit a three-run homer, Mitch Moreland added a two-run blast and Texas' dormant bats broke out in a big way as the Rangers spoiled Kendall Graveman's Oakland debut.
Adrian Beltre and Rougned Odor added solo home runs for Texas.
After being shut out twice in the first three games of the season, the Rangers scored eight runs in the first four innings to give Nick Martinez (1-0) plenty of support and earn a split of the season-opening four-game series.
Martinez gave up four hits in seven scoreless innings, his sixth straight start with two or fewer earned runs allowed. Graveman (0-1) had a brilliant first spring with the A's after being acquired in the offseason from Toronto in the Josh Donaldson deal. He allowed just one earned run in six starts and his 0.36 ERA was the lowest in the majors.
REDS 3, PIRATES 2
CINCINNATI (AP) - Joey Votto added to his resurgent series with his first homer since May 10, and Gregory Polanco's ninth-inning error sent Cincinnati past Pittsburgh for a season-opening sweep.
The Reds improved to 3-0 for the first time since 2011, when they won their first five games. The Pirates hadn't lost their first three games of a season since 2006, when they started 0-6 on the road.
Votto hit a tying two-run homer in the sixth inning. The 2010 NL MVP didn't play after July 5 last season because of strained muscles above his left knee. He was 5 for 14 with four RBIs in the series.
Todd Frazier led off the ninth with a double off Rob Scahill (0-1) and advanced on Devin Mesoraco's groundout. After Jay Bruce was intentionally walked, Polanco muffed Marlon Byrd's liner to right for a game-ending error. Aroldis Chapman (1-0) fanned two of the three batters he faced in the ninth.
Pedro Alvarez singled, homered and scored twice for the Pirates.
RED SOX 6, PHILLIES 2
PHILADELPHIA (AP) - Xander Bogaerts had three hits and three RBIs to back Justin Masterson in Boston's victory over Philadelphia.
Masterson (1-0) allowed two runs and three hits in six innings, striking out seven in his first start for the Red Sox since 2009. He also had a career-best two hits and an RBI.
The Red Sox won two of three in the interleague series and will move on to Yankee Stadium to face their AL East rivals.
Phillies right-hander David Buchanan (0-1) allowed six runs and seven hits in three innings.
The teams wore retro 1915 caps. The Red Sox beat the Phillies in the World Series that season.