STORRS, Conn. (AP) - Tiffany Hayes scored 22 points and No. 2 Connecticut recovered from its first loss in nearly 2 1/2 years with an 81-35 rout of Villanova on Wednesday night.
UConn saw its unprecedented record of 90 straight victories snapped at Stanford last Thursday.
Maya Moore added 16 for the Huskies (13-1, 3-0 Big East), who did set another record Wednesday night, winning their 70th straight home game.
UConn hasn't lost in Storrs or Hartford since being beaten by Rutgers 55-47 in the 2007 Big East tournament championship game. The NCAA counts both Big East and NCAA tournament games played by UConn at Gampel Pavilion and the XL Center as home games.
The 70th straight home win broke a tie with the record set by Tennessee from 1991-96 and matched by the Huskies from 2000-04. UConn.
Bria Hartley added 13 points and six rebounds for UConn, which fell to second in the Top 25 for the first time in 52 weeks on Monday. Moore, who played just 26 minutes, fell four points shy of reaching the 2,500 point-plateau for her career.
Lindsay Kimmel led Villanova (7-7, 0-2) with six points.
No. 6 West Virginia 67, Seton Hall 46
SOUTH ORANGE, N.J. (AP) - Liz Repella scored a season-high 24 points and No. 6 West Virginia survived an early second-half nap to remain undefeated with a victory over Seton Hall.
The Mountaineers (15-0, 2-0 Big East) saw an 18-point halftime lead dwindle to three points in less than seven minutes before Repella hit her fourth 3-pointer of the game to ignite a game-icing 15-point spurt.
Madina Ali added 10 points and 10 rebounds and Sarah Miles hit three layups in the late run to help West Virginia continue its best start in school history.
Jasmine Crew and Kandice Green scored 10 points apiece for Seton Hall (7-8, 0-2), which was limited to eight points in the final 13:21 by the nation's top defense.
No. 9 Xavier 83, Missouri 51
CINCINNATI (AP) - Center Ta'Shia Phillips had her eighth double-double of the season, repeatedly drawing fouls off power moves to the basket, and Xavier recovered from back-to-back losses by beating Missouri.
Xavier (11-2) was coming off road losses to Top 10 teams - one point at Duke and 37 points at Stanford - that ended the best start in school history.
The Musketeers haven't dropped three in a row since February 2004, and were never threatened by the Tigers (8-6). Phillips had 16 points and 15 rebounds, the cornerstone of an offense with four players in double figures. Phillips went 8 of 10 from the free-throw line.
At Duke, the Musketeers wasted a lead in the closing minutes. At Stanford, they buried themselves with a slow start. This one was in hand after an opening 18-4 run. RaeShara Brown led Missouri with 15 points.
No. 13 Notre Dame 73, Marquette 55
MILWAUKEE (AP) - Devereaux Peters scored 18 points to lead No. 13 Notre Dame to a victory over Marquette.
Peters came in averaging 9.8 points, but had 12 in the first half for Notre Dame (13-3, 2-0 Big East). She made 9 of 12 shots, grabbed eight rebounds, made four steals and blocked two shots as the Fighting Irish won their season-high eighth straight game.
Natalie Novosel added 14 points, including 10 during a decisive second half run for Notre Dame.
Tatiyiana McMorris scored 15 points to lead Marquette (12-3, 0-2) which shot 33.9 percent and had 24 turnovers.
Angel Robinson's jumper to open the second half pulled Marquette to 40-33, but then Notre Dame's defense took over. After Robinson's shot, the Golden Eagles went 1 for 15 with seven turnovers.
Novosel's 10 points sparked a 19-3 run capped by Skylar Diggins' two free throws that pushed the lead to 59-36 with 10:44 left to play.
No. 16 DePaul 71, Providence 38
CHICAGO (AP) - Katherine Harry scored 13 points to lead a balanced offense and No. 16 DePaul routed Providence.
The Blue Demons (14-2, 2-0 Big East) never trailed and opened an early 16-2 lead before the Friars (7-7, 0-2) made their first field goal. DePaul, which had been idle for two weeks, led 40-18 at halftime and by as many as 35 points in the second half.
Guard Sam Quigley scored 12 points for DePaul while Keisha Hampton added 11 points and a game-high eight rebounds. Guard Lola Wells topped the Friars with nine points.
No. 20 Ohio State 83, Indiana 65
COLUMBUS, Ohio (AP) - Samantha Prahalis broke out of a shooting slump with 23 points and Jantel Lavender had a career-high 22 rebounds to go with 22 points to lead Ohio State to a win over Indiana.
Prahalis made 9 of her 14 shots after missing 17 of her previous 21 over the last two games. Lavender's rebound total matched the third most in Ohio State history.
Tayler Hill added 12 points and Amber Stokes 10 for the Buckeyes (10-4, 1-1), the Big Ten's six-time defending champions who have been cold of late. They had lost four of six after climbing to No. 6 in The Associated Press poll after winning their first seven games.
Jori Davis had 21 points and Whitney Lindsay 20 for Indiana (8-7, 2-1).
No. 21 Iowa 63, Minnesota 57
MINNEAPOLIS (AP) - Kachine Alexander scored 20 points and Iowa rallied from a 13-point second-half deficit to beat Minnesota.
Iowa (13-3, 1-2 Big Ten) missed 13 of 14 shots late in the first half and trailed 38-25 when the comeback started. Kalli Hansen hit a 3-pointer to tie the score 53-53, then hit two free throws to put the Hawkeyes ahead for good.
Hansen also stole the ball with 11 seconds left with the Gophers setting up for a potential game-tying basket.
The victory ended a two-game skid for Iowa.
It was the second straight game that the Gophers squandered a second-half lead. They blew a ten-point advantage in an overtime loss to Indiana on Sunday and have lost their first three games of the Big Ten season.
Leah Cotton led Minnesota (8-8, 0-3) with 18 points.